Sample Preparation News

Clean Screen XCEL I Used to Confirm Fentanyl Overdose in Italian Case Study

Fentanyl, a well-known synthetic opioid approximately 100 times more potent than morphine, continues to be a public health issue. In cases of a fentanyl overdose, it is difficult to determine the cause of death based on toxicological information alone due...

Clean Screen® DAU cited in research on simultaneous analysis of Caffeine and metabolites by GCMS

Caffeine and its major metabolites; Theobromine, Theophylline and Paraxanthine are routinely monitored by anti-doping agencies as potential performance enhancers. Similar precursors and product ions of Theophylline and Paraxanthine makes the LCMS analysis of this panel very challenging. The aim of...

Strong cation Exchanger (BCX) cited in a study on a radiopharmaceutical for Neuroendocrine tumor

With a growing interest in clinical applications in recent years, the demand for Gallium-68 (68Ga) has also increased. 68Ga-DOTATATE is used as a radiotracer in Positron Emission Tomography (PET) to detect and evaluate cancer-causing Neuroendocrine tumor (NET) cells. A particle accelerator, Cyclotron,...

A New Single-Laboratory Validated Method for the Detection of Pyrethroid Metabolites in Milk by GC/MS

With concerns over the household use of pyrethroid pesticides for mosquito control, researchers in Thailand have developed a validated method for analyzing cis/trans-permethrinic acid in powdered milk. Pyrethroids are naturally occurring pesticides that are synthesized to manufacture mosquito coils and...

Importance of umbilical cord analysis in determining prenatal drug exposure

Fentanyl serves as a powerful analgesic agent to manage pain during labor and delivery. However, prolonged prenatal exposure can make babies drug dependent and sudden discontinuation may result in conditions like Neonatal Abstinence Syndrome (NAS) or Neonatal Opioid Withdrawal Syndrome...

XtrackT SPE column used in research work focused on doping control in horse racing

The major metabolite of Dopamine, 3-methoxytyramine (3-MT) is monitored in equine urine samples as an indicator of dopaminergic manipulation from Levodopa administration. Tyramine is a biogenic amine produced by decarboxylation of amino acid L-Tyrosine. Changes in the diet could alter...

Sri Lankan Folk Medicine Could Save Lives

The terpene-filled plant, Plectranthus zeylanicus Benth can be found growing in the hills of Sri Lanka and has been used in Sri Lankan folk medicine as a treatment for inflammation and microbial infections.  A team of international researchers has been...

UCT’s DAU column cited in a Study on Postmortem Quantitation of Amphetamine

In a recent article published in the MDPI journal, authored by Ahmed I. Al-Asmari et al., UCT’s Clean Screen® DAU column (CSDAU203) was employed to extract Amphetamines from cadaveric fluids. The objective of this research was to conduct an epidemiological...

Analyzing pesticides and metal(loid)s in imported tobacco to Saudi Arabia and risk assessment of inhalation exposure to certain metals

Researchers at the Reference Laboratory for Food Chemistry, Saudi Food & Drug Authority (SFDA), Riyadh, Saudi Arabia, have discovered more toxins in cigarettes than previously thought. The researchers analyzed 60 tobacco samples from 8 popular cigarettes brands commercially available in...

Pharmacokinetic Evaluation of a Cannabidiol Supplement in Horses

A new study led by researchers at Oklahoma State University focuses on a better understanding of the pharmacokinetics of orally administered cannabidiol in horses. With the growing popularity of cannabidiol products in the equine industry, it becomes necessary to comprehend...