Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly implemented in the treatment of inflammation, pain and fever when used in therapeutic doses in human and veterinary medicine. The use of NSAIDs in racehorses is tightly regulated because of their ability to influence the performance of horses. For this reason, International Federation of Horseracing Authorities (IFHA) published a range of screening limits for prohibited substances that can be used as therapeutics agent in racehorses.
The published method by the Doping Control Laboratory, Istanbul, Turkey provides for the simultaneous determination of nine non-steroidal anti-inflammatory drugs known as therapeutic prohibited substances in equine urine. It has been developed and fully validated according to the European Commission Decision 2002/657/EC and Association of Official Racing Chemists(AORC) criteria.
The efficiency of the confirmatory method that utilized UCT’s XtrackT® C18 Cartridges was shown within the study of all passing validation parameters. Results were matching the criteria in the 2002/657/EC directive and AORC requirements. The real sample results demonstrated the usefulness of the method for doping control laboratories in future research and assessment. Download and view the full article presented in the latest edition of Drug Testing and Analysis here: https://onlinelibrary.wiley.com/doi/abs/10.1002/dta.2864.