Congratulations to Sara McGrath at the FDA Center for Food Safety and Applied Nutrition for winning the 2017 NACRW Excellence in Sample Prep Award!
Designer benzodiazepines are among the most prevalent Novel Psychoactive Substances (NPS) on the modern drug market. These designer drugs are synthesized to mimic the structure and effects of traditional benzodiazepines. Research and literature on the pharmacological effects of designer benzodiazepines are lacking, but they are generally more potent than their traditional counterparts. The numerous and…
Marilyn J Schneider, Steven J Lehotay, and Alan R Lightfield at the US Department of Agriculture recently published a paper in the journal Analytical and Bioanalytical Chemistry.
Fentanyl, a well-known synthetic opioid approximately 100 times more potent than morphine, continues to be a public health issue. In cases of a fentanyl overdose, it is difficult to determine the cause of death based on toxicological information alone due to the tolerance of habitual users and significant post-mortem redistribution. An Italian group published a…
UCT is known around the world as the first company to commercialize the QuEChERS ((Quick, Easy, Cheap, Effective, Rugged, and Safe) approach and is proud to support facilities involved in food safety testing using this technique. In a new paper published in Journal of Agricultural and Food Chemistry (DOI: 10.1021/acs.jafc.6b05051) by S. Genualdi et al., (U.S. Food and Drug Administration, Maryland, USA) the simultaneous analysis of 3- monochloropropane-1,2-diol (3-MCPD) and 1,3 dichloropropane-2-ol (1,3-DCP) was executed in asian style sauces. In this report UCT’s extraction mylar pouches (AOAC Blend) which include 6 g MgSO4 with 1.5 g of sodium acetate and dSPE clean-up pouches containing 400 mg of PSA and 400 mg of C18 were employed to perform the QuEChERS extraction prior to analysis of 3-MCPD and 1,3-DCP. This new method utilized direct analysis of the extract without derivatization using gas chromatography-triple quadrupole mass spectrometry (GC-MS/MS). The developed method was applied to 60 genuine soy sauce samples to determine if concentrations have changed since the FDA limit was set in 2008.
The terpene-filled plant, Plectranthus zeylanicus Benth can be found growing in the hills of Sri Lanka and has been used in Sri Lankan folk medicine as a treatment for inflammation and microbial infections. A team of international researchers has been working to isolate the bioactive ingredients of this plant. Previous investigations have found potent 5-LO…
UCT Inc., is well-known for its commitment to support in the area of environmental analytical research. In a recent paper published in Science of The Total Environment by J-H Lee and J-H Oh ((2016) 556: 330-337), UCT’s Enviro-Clean 521 cartridges were used to extract nitrosoamines from water samples originating in sewerage water plants.
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