Dextromethorphan and Dextrorphan Recovery from Skeletal Tissue Investigated

August 5th, 2015 Sample Preparation News

The article, published in the journal Drug Testing and Analysis is titled ‘Analysis of dextromethorphan and dextrorphan in decomposed skeletal tissues by microwave assisted extraction, microplate solid-phase extraction and gas chromatography – mass-spectrometry (MAE-MPSPE-GSMS)’, DOI: 10.1002/dta.1754.

Dextromethorphan is an antitussive compound that has abuse potential; dextrorphan is its primary metabolite.  Investigators were studying the recovery of these compounds from skeletal tissue following microwave assisted extraction.  UCT’s CLEAN SCREEN XCEL® I sorbent was used to clean up the sample extracts prior to GC-MS analysis.   The method showed excellent analyte recovery, linearity and sensitivity.

UCT is a leading manufacturer of sample preparation and chromatography products for the forensic market.  Contact us to learn more about how we can help you and any challenging analyses you have.

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