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Dynein-Powered Cell Locomotion Guides Metastasis of Breast Cancer

Metastasis of cancer cells is the primary cause of death in cancer patients and continues to be one of the most difficult clinical problems. There are many theories about how metastasis occurs, but the main aspects have been linked to...

GC–MS Analysis of Soil Faecal Biomarkers Uncovers Mammalian Species and the Economic Management of the Archeological Site

While United Chemical Technologies is most well-known for our high-quality solid phase extraction products and specialty silanes, silicones, and siloxanes, we also provide high-quality derivatizing reagents (DRs), with a wide variety of scientific applications. While DRs, such as UCT’s SBSTFA,...

Per-Aqueous Liquid Chromatography for the Separation of Polar Compounds‑Preparation and Characterization of Poly (ethylene oxide‑co‑dimethylsiloxane) Based Stationary Phase

United Chemical Technologies is widely known for our high-quality solid phase extraction products and stationary phases. Though we full equipped to make custom bonded phases for clients, we love to see what researchers discover on their own. A research group...

Physicochemical Properties Predict Retention of Antibiotics in Water-in-Oil Droplets

The ability to study antibiotic resistant pathogens by using methods such as antimicrobial susceptibility testing (AST) is important, especially with the rapid emergence of more and more antibiotic resistant pathogens. AST is a method with uses droplets of solutions as...

Testing of drugs using human feto-maternal interface organ-on-chips provide insights into pharmacokinetics and efficacy

There are a very limited number of medical interventions to prevent placental-mediated adverse pregnancy outcomes, such as preterm birth (PTB) and no interventions available for pre-eclampsia (PE). This is because pharmaceuticals are unable to cross feto-maternal interface (FMi) barriers and...

High-Resolution Optical Tweezers Combined with Multicolor Single-Molecule Microscopy

Optical tweezers (OT) are a device that can manipulate individual molecules with cells by using light from low-wattage lasers and are used to study and manipulate DNA and RNA. There is a serious limitation to these optical tweezers. They can...

The shape of pleomorphic virions determines resistance to cell-entry pressure

The study of viruses is a never-ending battle. Even for well-studied viruses such as the influenza A virus, scientists are continuing to discover new data. A research group in Brandeis University has begun to study the particle structure of viruses...

An Electrochemiluminescence Biosensor for Detection of CdkN2A/p16 Anti-oncogene Based on Functional Electrospun Nanofibers and Core-shell Luminescent Composite Nanoparticles

In the pursuit of cancer research and clinical applications, one of the most important factors is the recognition and quantitation of the CdkN2A/p16 anti-oncogene, AKA the multiple tumor suppressor 1 gene (MTS1). This gene is associated with metastatic spread of...

Myelination and Node of Ranvier Formation in a Human Motoneuron−Schwann Cell Serum-Free Coculture

Motor neurons allow the body to move, speak, and breathe due to the propagation of action potentials between neuron nodes. The space between neurons, known as a node of Ranvier, are protected by a myelin sheath. When these nodes or...

Silane Coupling Agent Modifies the Mechanical Properties of a Chitosan Microfiber

Microfiber materials have been widely used for many applications, in the medical field, such as in sutures. Chitosan fibers, along with chitin fibers, are candidates for similar biofibers due to stronger inherent mechanical properties, however the current synthesis of these...