Specialties Chemicals News

High-Resolution Optical Tweezers Combined with Multicolor Single-Molecule Microscopy

Optical tweezers (OT) are a device that can manipulate individual molecules with cells by using light from low-wattage lasers and are used to study and manipulate DNA and RNA. There is a serious limitation to these optical tweezers. They can...

The shape of pleomorphic virions determines resistance to cell-entry pressure

The study of viruses is a never-ending battle. Even for well-studied viruses such as the influenza A virus, scientists are continuing to discover new data. A research group in Brandeis University has begun to study the particle structure of viruses...

An Electrochemiluminescence Biosensor for Detection of CdkN2A/p16 Anti-oncogene Based on Functional Electrospun Nanofibers and Core-shell Luminescent Composite Nanoparticles

In the pursuit of cancer research and clinical applications, one of the most important factors is the recognition and quantitation of the CdkN2A/p16 anti-oncogene, AKA the multiple tumor suppressor 1 gene (MTS1). This gene is associated with metastatic spread of...

Myelination and Node of Ranvier Formation in a Human Motoneuron−Schwann Cell Serum-Free Coculture

Motor neurons allow the body to move, speak, and breathe due to the propagation of action potentials between neuron nodes. The space between neurons, known as a node of Ranvier, are protected by a myelin sheath. When these nodes or...

Silane Coupling Agent Modifies the Mechanical Properties of a Chitosan Microfiber

Microfiber materials have been widely used for many applications, in the medical field, such as in sutures. Chitosan fibers, along with chitin fibers, are candidates for similar biofibers due to stronger inherent mechanical properties, however the current synthesis of these...

A Circular Gradient-Width Crossflow Microfluidic Platform for High-Efficiency Blood Plasma Separation

Clinical diagnostic tests use blood plasma for detecting the biomarkers of illnesses such as diabetes, cancer, and many others. Blood plasma makes up about half of the make up of whole blood and the separation of plasma is both labor...

Magnetically-Actuated Microposts Stimulate Axon Growth

New research published in the Biophysical Journal introduces a new method utilizing magnetically-actuated microposts as a scaffold for the stimulation of axon regeneration. These non-toxic, magnetic microposts, synthesized using tridecafluorooctyltrichlorosilane (United Chemical Technologies PART # T2492) as a mold release agent, were...

UCT’s Trichlorosilane Integral in Antibody Success Evaluation in Model Viral Agent, Murine Coronavirus

Identifying antibodies (Abs) that neutralize infectious agents is the first step for developing therapeutics, vaccines, and diagnostic tools for infectious agents. However, current approaches for identifying neutralizing Abs (nAbs) typically rely on dilution-based assays that are costly, inefficient, and only...

UCT Specialty Chemical Cited in Microalgae Study

Microalgae are promising alternatives to petroleum as renewable biofuel sources, however not sufficiently economically competitive yet. In a recent paper published in Lab On A Chip ((2019) 19 4128) authored by Song-I Han et al., UCT’s specialty chemical tridecafluoro-1,1,2,2- tetrahydrooctyl-1-trichlorosilane...

UCT Silane Cited in Droplet-Based Microfluidic Article

The kidneys are considered critical for the long-term control of blood pressure by regulation of body fluid and blood volume. In support of this concept, the kidneys control the systemic activity of the pro-hypertensive renin-angiotensin-aldosterone system by regulating the production...