Clinical diagnostic tests use blood plasma for detecting the biomarkers of illnesses such as diabetes, cancer, and many others. Blood plasma makes up about half of the make up of whole blood and the separation of plasma is both labor and time intensive. A group of researchers from Texas A&M University have designed a microfluidic device for highly efficient separation of blood plasma utilizing United Chemical Technology’s (tridecafluoro-1,1,2,2 tetrahydrooctyl) trichlorosilane (PRODUCT # T2492) as a protective coating for the design of the channels on the microfluidic device. The researchers found that their microfluidic device exhibited higher recovery rate, lower levels of hemolysis and less channel clogging due to red blood cells than other similar devices and could be applied to clinical applications soon.
Citation: Zhang, H.; Anoop, K.; Huang, C.; Sadr, R.; Gupte, R.; Dai, J.; Han, A., A Circular Gradient-Width Crossflow Microfluidic Platform for High-Efficiency Blood Plasma Separation, Sensors and Actuators B: Chemical, 2022, 354, 131180.
(tridecafluoro-1,1,2,2 tetrahydrooctyl) trichlorosilane (T2492)