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Top 10 Forensic Compounds/Topics of 2016 – Opiate Derivatization
Multiple strategies can be used to derivatize opiates prior to analysis on GC-MS. A variety of both silylation and acylation reagents can be used to best accomplish this, including either BSTFA (with 1% TMCS) or Propionic Anhydride (PIA).
UCT’s DETA cited in Stem Cell Research Study
In a recent paper authored by Navaneetha Santhanam et al, published in Biomaterials ((2018) 166 64-78), UCT’s specialty chemical 3-trimethoxysilyl propyl diethylenetriamine (DETA), an amine-terminated alkylsilane, was employed to promote cell adhesion. This study was designed to develop and evaluate a prototype of a drug-screening platform for neuromuscular junctions at different modes of operation: presynaptic and/or postsynaptic
UCT Clean Screen® DAU Cited in Novel Fentalogs Article
Methoxyacetylfentanyl and cyclopropylfentanyl are two of the newest illicit opioids that are infiltrating the heroin market. They both have been reported by the Drug Enforcement Administration in their third quarter report of 2017 to have been chemically identified seven and five times, respectively. In a recent paper authored by Melissa F. Fogarty et al., published in Journal of Analytical Toxicology (doi: 10.1093/jat/bky035), an analytical method was developed and validated to extract fentalogs from whole blood samples using UCT’s Clean Screen ® DAU. The method used LC-MS/MS for the quantitation of fentanyl, norfentanyl and 17 fentanyl analogs.
CLEAN SCREEN® THC SPE Columns Used for the Extraction of 37 Synthetic Cannabinoid Metabolites
Researchers at the Republic of Korea National Forensic Service have recently published an article in the journal of the Japanese Association of Forensic Toxicology titled ‘Simultaneous quantification of 37 synthetic cannabinoid metabolites in human urine by liquid chromatography-tandem mass spectrometry’ (doi 10.1007/s11419-015-0265-x).
UCT Clean Screen DAU cited in Postmortem Toxicology Article
The United Nations Office on Drugs and Crime (UNODC) estimated that 76% of drug related fatalities during 2016 were related to the misuse of opioids. The UNODC also reported that the production of opium and cocaine are at the highest levels ever recorded, with the distribution of methamphetamine and cocaine expanding to new regions. The…
UCT featured in Select Science article, “11 Methods to Ensure Food Safety.”
UCT has been featured in Select Science article, “11 Methods to Ensure Food Safety” with the recently released ‘Patulin Analysis in Apple Juice’ application. View the Select Science featured article and patulin application note here: http://bit.ly/1Vx47BT