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Optimization of NPS sample preparation in blood, urine, serum, and plasma

Optimization of NPS sample preparation in blood, urine, serum, and plasma

ByUCT

New/Novel Psychoactive Substances (NPSs) are newly emerging, rapidly developing compounds designed to mimic the intoxicating effects of illicit substances. The ever-changing landscape of the NPS market and the varying physiochemical properties of these compounds make developing and validating up-to-date analytical methods a challenge. Different extraction and derivatization procedures were assessed to determine an optimal procedure…

Tracking Novel Psychoactive Substances in Australia: The Power of Wastewater-Based Epidemiology with SPE and LC-MS-MS

Tracking Novel Psychoactive Substances in Australia: The Power of Wastewater-Based Epidemiology with SPE and LC-MS-MS

ByUCT

New Psychoactive Substances (NPS) are synthetic drugs not regulated under the 1961 or 1971 Conventions, posing significant public health risks. Monitoring NPS is essential for public health, regulatory action, scientific research, and addressing community and environmental impacts. Wastewater-based epidemiology (WBE) is a key method for studying these substances, combining toxicology, environmental science, and analytical chemistry…

Effect of Cold-Pressing on Phytochemical Composition, Antioxidant, and Sensory Properties of Broccoli, Amaranth, and Red Beet Microgreen Juices
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Effect of Cold-Pressing on Phytochemical Composition, Antioxidant, and Sensory Properties of Broccoli, Amaranth, and Red Beet Microgreen Juices

ByUCT

Microgreens have gained popularity due to their abundant nutritional content, providing a diverse range of vitamins, minerals, and phytonutrients. They are harvested at an early stage, typically within a few weeks of germination when they are just a few inches tall and have developed their first true leaves. Recently, there has been interest in microgreen…

The Analysis of Two Common Analgesic Drugs in Wastewater: Paracetamol (Acetaminophen) and Diclofenac
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The Analysis of Two Common Analgesic Drugs in Wastewater: Paracetamol (Acetaminophen) and Diclofenac

ByUCT

With diluted wastewater discharge being used as a source of drinking water in many locations throughout the world, it should be of concern which medications are commonly found in our wastewater. Researchers at the Institute of Environmental Technology, Vietnam Academy of Science & Technology have published a method for the determination of two common analgesics…

Clean Screen XCEL I Used to Confirm Fentanyl Overdose in Italian Case Study
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Clean Screen XCEL I Used to Confirm Fentanyl Overdose in Italian Case Study

ByUCT

Fentanyl, a well-known synthetic opioid approximately 100 times more potent than morphine, continues to be a public health issue. In cases of a fentanyl overdose, it is difficult to determine the cause of death based on toxicological information alone due to the tolerance of habitual users and significant post-mortem redistribution. An Italian group published a…

Importance of umbilical cord analysis in determining prenatal drug exposure
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Importance of umbilical cord analysis in determining prenatal drug exposure

ByUCT

Fentanyl serves as a powerful analgesic agent to manage pain during labor and delivery. However, prolonged prenatal exposure can make babies drug dependent and sudden discontinuation may result in conditions like Neonatal Abstinence Syndrome (NAS) or Neonatal Opioid Withdrawal Syndrome (NOWS). Adequate literature on the suitability of umbilical cord as a specimen for drug testing…