plasma

Optimization of NPS sample preparation in blood, urine, serum, and plasma

Optimization of NPS sample preparation in blood, urine, serum, and plasma

New/Novel Psychoactive Substances (NPSs) are newly emerging, rapidly developing compounds designed to mimic the intoxicating effects of illicit substances. The ever-changing landscape of the NPS market and the varying physiochemical properties of these compounds make developing and validating up-to-date analytical methods a challenge. Different extraction and derivatization procedures were assessed to determine an optimal procedure…

Investigation of Transdermal Buprenorphine Patch for Use on Horses
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Investigation of Transdermal Buprenorphine Patch for Use on Horses

Transdermal administration of buprenorphine via a patch has been investigated in animals such as dogs, cats, pigs, sheep, and primates. Paranjape VV. et al to their knowledge are the first to describe the use on horses. This study monitored the physiological conditions and pharmacokinetic profile of six horses under three different rounds of treatments. BUP0…