UCT MSTFA Derivatizing Reagent Cited in Archaeological Study

October 23rd, 2017

The determination of original source of use-related residues on prehistoric stone tools is especially challenging, due to issues related to preservation, contamination and multiple source residue the contributions. To increase confidence in this process, an analytical workflow was developed by Susan Luoing et al., published in Analytical Methods (2017, 9, 4349) which included a sampling strategy that retains spatial information of the recovered residues and enables monitoring of environmental contamination; and a sensitive and selective gas chromatography-tandem mass spectrometry (GC-MS/ MS) procedure to quantify non-volatile low molecular weight lipids on stone artefacts. Representative aliquots were spiked with internal standards.  After extraction of the lipids and evaporation of the extracts, the samples were derivatized with UCT’s MSTFA (N-Methyl-N-trimethylsilyltrifluoroacetamide) containing 1%TCMS (1% trimethylchlorosilane) silylation reagent.