Dextromethorphan

UCT’s Clean Screen® Xcel 1 SPE 96 Well Plates Cited in Animal Study

UCT’s Clean Screen® Xcel 1 SPE 96 Well Plates Cited in Animal Study

The correlation of drugs in decomposed human remains and animals is very useful for forensic toxicologists working with complex matrices that go beyond post mortem samples.  In a recent paper published in Journal of Analytical Toxicology, Lucas M. Morrison et al.,(doi: 10.1093/jat/bkx040)  employed UCT’s famous Xcel I SPE sorbent to extract Dextromethorphan (DXM) and its primary metabolite (DXT) from the remains of rats. They analyzed DXM and DXT in skeletal remains of rats following acute (ACU, 75 mg/kg, IP, n = 10) or three repeated (REP, 25 mg/kg, IP, n = 10, 40-minute intervals) doses of DXM.