Clean Up Covalent

Clean Up Covalent

For international ordering, contact your International Distributor.

For sample requests, please contact your Regional Sales Representative

MECHANISM OF COVALENT BONDING

Covalent sorbents have either epoxy, aldehyde, isocyanate or thiopropyl functional groups that are bound to the silica backbone by a hydrocarbon chain.  These groups will react selectively with analyte functional groups causing a formal bond between the stationary support and the analyte.

 In the case of the aldehyde sorbent, an analyte with a primary amine performs a nucleophilic attack on the aldehyde functionality in the sorbent.  This attack results in a Schiff base, with the amine immobilized on the stationary support.  This chemistry can be utilized to bind proteins, such as antibodies, to the support, allowing highly specific extractions.

 The thiopropyl functional group scavenges for alkylating agents, alcohols and amines.

 Thiopropyl is the only stock product available, contact UCT for other covalent chemistry availabilities.

Order Clean Up Covalent Products

ImagePart NumberDescriptionCategoriesNarrow By IndustrySizeColumnUnitsPriceBuyhf:categorieshf:att:pa_industryhf:att:pa_sizehf:att:pa_column
Covalent Sorbent -Thiopropyl-0
CUTHX123Clean-Up Thiopropyl 200mg 3mLCovalent Sorbent -ThiopropylPharmaceutical & Biotech200350$150.00
clean-up-thiopropyl clean-up-covalent silica spe9d-pharmaceuticalbiotech21-2006d-3