Founded in 1986 in Horsham, PA, United Chemical Technologies, Inc. (UCT, Inc.) has grown from a manufacturer of solid phase extraction sorbents into a major competitor in the fields of specialty chemicals, chromatographic media and sample preparation products. UCT began with a novel technological idea for solid phase extraction (SPE): bond two different functional groups to a solid support material in order create phases that are capable of extracting samples based on different chemical principles. The first product was our CLEAN SCREEN® DAU. This product incorporated an ion exchange functionality with a hydrophobic alkyl chain. This product was quickly adopted in analytical labs and is now the most widely used SPE material in the clinical and forensic industry for the clean extraction of biological matrices.
UCT Silane (TSPS) cited in Microbiology Article
Numerous polymerase-chain-reaction (PCR) and isothermal amplification methods employed currently in molecular diagnostic assays have been developed, significantly improving assay sensitivity and specificity as well as shortening overall time. In spite of this objective, nucleic acid target amplification continues to present challenges for dealing with “false-positive” results due to environmental or reagent contaminants introduced during the testing process. This has been addressed in a recent article authored by Wanyuan Ao et al., published in PLoS ONE 12(2): e0171915 in which UCT silane amine-functional T-structure polydimethylsiloxane (TSPS) was described in the production of crystalline silicon wafers. In this paper, the authors describe a strategy that can distinguish between staphylococcus species truly present in a clinical sample from contaminating staphylococcus species introduced during the testing process.