UCT Flagship Sorbent Clean Screen® Cited in Synthetic Cathinones Study
In recent years, the abuse of newer psychoactive substances (NPS) such as synthetic cathinones or ‘bath salts’ has become a major public health concern. These compounds were initially sold legally and labeled “not for human consumption.” Three popular drugs of this type are methylone, mephedrone, and 3, 4-methylenedioxypyrovalerone (MDPV). Unfortunately, there is currently no information available on the teratogenicity of these compounds, or of the extent to which they cross the placenta. In a recent paper authored by Lauren G. Strange et al., published in the journal Neurotoxicology and Teratology ((2017) 63 9–13) this issue was addressed by employing UCT’s flagship sorbent Clean Screen® DAU followed by analysis utilizing HILIC LC-MS/MS. The purpose of this study was to examine the pharmacokinetic profile of the ‘bath salts’ in a pregnancy model using an animal model.