Myelination and Node of Ranvier Formation in a Human Motoneuron−Schwann Cell Serum-Free Coculture
Motor neurons allow the body to move, speak, and breathe due to the propagation of action potentials between neuron nodes. The space between neurons, known as a node of Ranvier, are protected by a myelin sheath. When these nodes or sheaths, become damaged, they lead to demyelinating neuropathies such as schizophrenia, multiple sclerosis, Guillain-Barre syndrome…