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An Electrochemiluminescence Biosensor for Detection of CdkN2A/p16 Anti-oncogene Based on Functional Electrospun Nanofibers and Core-shell Luminescent Composite Nanoparticles
In the pursuit of cancer research and clinical applications, one of the most important factors is the recognition and quantitation of the CdkN2A/p16 anti-oncogene, AKA the multiple tumor suppressor 1 gene (MTS1). This gene is associated with metastatic spread of tumor cells, which, in general terms, the higher the quantified amount of this gene, the…
UCT Frits Cited in Prenatal Tobacco and Alcohol Study
Tobacco and alcohol use during pregnancy is a serious public health concern, resulting in adverse obstetrical and neonatal outcomes including miscarriage, preeclampsia, low birth weight, preterm delivery, fetal growth restriction, decreased head circumference, placenta abruption, and facial abnormalities. Meconium is a good matrix for in utero drug exposure assessment in pregnancies carried to term. Although meconium formation begins as early as 13 weeks, other methods must assess earlier exposure. In this study, we examined whether analysis of fetal liver and placenta from electively terminated pregnancies utilizing solid-phase extraction could determine exposure patterns during the second trimester.
6PPD, Salmon, and Tires
You probably know what salmon and tires are, but have you ever heard of 6PPD? How about 6PPD-q? 6PPD stands for N-(1,3-dimethylbutyl)-N’-phenyl-p-phenylenediamine. When this compound is exposed to air, ozone reacts with 6PPD to form its quinone, 6PPD-q. How about salmon and tires? 6PPD is a tire stabilizer that prevents tires from breaking down. As…
Mushrooms for Memory?
Researchers worldwide have been studying Hericium erinaceus [1] (also called lion’s mane mushroom, mountain-priest mushroom, or bearded tooth fungus). This magical mushroom is common throughout North America, Europe, and Asia and can be seen growing on dead American beech and maple trees in late summer and autumn. Most research involves testing how various compounds extracted…
Clean Screen® DAU Used in Heroin-related Death Study Conducted in Jeddah, Saudi Arabia
Drug trends in some regions of the world are extensively studied while in other regions little to no research has been done. For example, countless studies have been performed in the United States of America while in the midst of its opioid epidemic. Meanwhile, in the Arabian Gulf region, only a few studies have been…
Biochemical Chemical Compounds and Stress Markers in Lettuce upon Exposure to Pathogenic Botrytis cinerea and Fungicides Inhibiting Oxidative Phosphorylation
Chemical protection of plants is necessary to maximize crop yields. Consequently, using pesticides can disrupt the concentrations of biochemical compounds in plants and reduce the availability of essential plant nutrients available to the human diet. Researchers at the Institute of Plant Protection – National Research Institute in Poland have recently published a paper showing how…