Sample Preparation News

Dextromethorphan and Dextrorphan Recovery from Skeletal Tissue Investigated

The article, published in the journal Drug Testing and Analysis is titled ‘Analysis of dextromethorphan and dextrorphan in decomposed skeletal tissues by microwave assisted extraction, microplate solid-phase extraction and gas chromatography – mass-spectrometry (MAE-MPSPE-GSMS)’, DOI: 10.1002/dta.1754. Dextromethorphan is an antitussive compound that has abuse...

Endcapped C18 Helps Researchers Achieve Excellent Analyte Sensitivity and Recovery for 131 Drug Residues in Bovine Muscle

The article, titled “Validation of a streamlined multiclass, multiresidue method for determination of veterinary drug residues in bovine muscle by liquid chromatography-tandem mass spectrometry” (DOI: 10.1007/s00216-014-8386-3) uses a d-SPE technique for the extraction of 131 veterinary drug residues in bovine muscle...

CLEAN SCREEN® THC SPE Columns Used for the Extraction of 37 Synthetic Cannabinoid Metabolites

In the method the authors used UCT’s CLEAN SCREEN® THC solid phase extraction (SPE) cartridges for the extraction of the cannabinoid metabolites from urine samples.  The SPE extractions helped researchers achieve LOD’s ranging from 0.1 to 1ng/mL, matrix effects biases ranging...

Newly published US EPA method 625.1 allows for solid phase extraction of semivolatile organic pollutants in industrial discharges

This technique requires multiple extractions at 2 different sample pHs and consumes large amounts of organic solvents. EPA method 625.1, an updated version of method 625 has been recently published (by Lemuel Walker, Office of Science and Technology, US EPA)...

Selectra® PFPP Column Used in NIDA Paper Examining Cannabinoids in Oral Fluids

In the method the authors used a UCT Selectra® PFPP HPLC column for the analysis.  The unique phase provided the researches with the selectivity they needed with excellent peak shape and run times.  The LOQ’s for all compounds examined were 0.2µg/mL,...

Clean Screen DAU Used for Extraction of Propofol from Blood Samples

The article was published in Analyst, 2015,140, 98 (doi: 10.1039/c4an01483a).  The article describes a new membrane coated voltammetric sensor blood monitoring device for the detection of propofol in blood.  For testing and comparison purposes the authors compared device results with...

Incorporation of Clean Screen FASt® extraction in the study of ZCZ-011 in mouse brain tissue helps minimize and stabilize matrix ion suppression effects

Researchers at the Virginia Commonwealth University (Richmond, VA, USA), University of Aberdeen (Aberdeen, U.K.) and the University of Toronto (Toronto, Canada) have developed a novel pharmacological tool for the investigation of the cannabinoid receptor in mouse brain tissue using HPLC-MS-MS...