UCT featured in Select Science article, “11 Methods to Ensure Food Safety.”

ByUCT

UCT has been featured in Select Science article, “11 Methods to Ensure Food Safety” with the recently released ‘Patulin Analysis in Apple Juice’ application. Patulin is a naturally occurring mycotoxin that is produced by several species of fungi, such as Penicillium and Byssochlamys, and has been implicated as a possible carcinogen and teratogen, although an official designation has not yet been made. The application note outlines a simple solid-phase extraction (SPE) procedure for the low level detection of patulin in apple juice. View the Select Science featured article and patulin application note here: http://bit.ly/1Vx47BT

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UCT Clean Screen® DAU Cited in Umbilical Cord Drug Testing Article

UCT Clean Screen® DAU Cited in Umbilical Cord Drug Testing Article

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Analysis of umbilical cord samples offers forensic toxicologists a method for evaluating maternal drug intake patterns. These matrices may be an uncommon sample for many laboratories, but for those that are tasked with the challenge, solid phase extraction offers the most efficient methodology for the analysis of said compounds.

In recent paper authored by Amy Alexander et al., in Journal of Analytical Toxicology (doi: 10.1093/jat/bky009), UCT’s flagship sorbent Clean Screen®DAU (CSDAU020) was employed to analyze samples of umbilical cord taken from two monozygotic twins. It was found that the umbilical cord from newborn #1 was positive for hydromorphone only (1.06 ng/g), and the umbilical cord from newborn #2 was positive for hydromorphone (0.81 ng/g) and benzoylecgonine (5.41 ng/g).

Clean Screen® DAU Featured in Method to Analyze Xylazine, p-Fluorofentanyl, Fentanyl, and Fentanyl-Related Compounds in Postmortem Blood
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Clean Screen® DAU Featured in Method to Analyze Xylazine, p-Fluorofentanyl, Fentanyl, and Fentanyl-Related Compounds in Postmortem Blood

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The presence of xylazine continues to be on the rise in samples containing fentanyl or fentanyl-related substances. A recent method published in the Journal of Chromatography B uses SPE and LC/MS-MS to quantitate xylazine, 4-ANPP, acetyl fentanyl, fentanyl, norfentanyl, and p-fluorofentanyl. Xylazine is rarely abused on its own, and research suggests it has effects comparable…

The Analysis of Two Common Analgesic Drugs in Wastewater: Paracetamol (Acetaminophen) and Diclofenac
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The Analysis of Two Common Analgesic Drugs in Wastewater: Paracetamol (Acetaminophen) and Diclofenac

ByUCT

With diluted wastewater discharge being used as a source of drinking water in many locations throughout the world, it should be of concern which medications are commonly found in our wastewater. Researchers at the Institute of Environmental Technology, Vietnam Academy of Science & Technology have published a method for the determination of two common analgesics…

UCT Flagship Clean Screen® DAU cited in NPS Article

UCT Flagship Clean Screen® DAU cited in NPS Article

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UCT is well-recognized for its flagship solid phase extraction (SPE) sorbent Clean Screen® DAU. This acclaimed sorbent is employed by many forensic toxicology laboratories for the extraction of drugs and metabolites from biological matrices, including the increasingly encountered novel psychoactive substances (NPS). In a new paper authored by C.Mitchell-Mata in Journal of Analytical Toxicology (doi: 10.1093/jat/bkx048), CSDAU206 was used to extract 3- and 4-methoxyphencyclidine (3-MeO-PCP, 4-MeO-PCP) in forensic cases.

Opiate/Opioid Analysis Using UCT SPE Sorbents

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The abuse of and addiction to opioids and opiates such as morphine, codeine, and hydrocodone is a serious global problem that affects the health, social, and economic welfare of all societies around the world.  It has been estimated that between 26.4 million and 36 million people abuse opioids worldwide, with an estimated 2.1 million people in the United States suffering from substance use disorders related to prescription opioid pain relievers. UCT has been at the forefront of toxicological analysis of opiates (those compounds originating from the poppy plant), and opioids (compounds structurally related to morphine but produced synthetically e.g hydromorphone, oxycodone, and oxymorphone) using its world renowned Clean Screen® DAU and XtrackT® sorbents.

UCT Flagship Sorbent Cited in Synthetic Fentanyl Analysis Article

UCT Flagship Sorbent Cited in Synthetic Fentanyl Analysis Article

ByUCT

In a recent paper authored by Kraig E. Strayer et al., published in ACS Omega ((2018) 3 514-23), UCT’s famous flagship sorbent Clean Screen ® DAU was employed to extract fentanyl analogs from whole blood. The authors describe the development and validation of a solid phase extraction (SPE) process combined with liquid chromatography tandem mass spectrometry-based method for the multiplex detection of  24 illicitly manufactured fentanyl analogues and metabolites in whole blood at concentrations as low as 0.1−0.5 ng per mL using the UCT sorbent. 

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