It goes without saying that fentanyl related overdoses and deaths were a major public health issue across the United States in 2016 and will continue to be in the upcoming year. Forensic toxicologists need fast and accurate extraction methodologies in order to not only identify fentanyl but also additional novel analgesics that may be isolated in casework screening protocols. UCT’s Clean-Screen® XCEL I solid phase extraction columns allow for the elimination of conditioning steps and the reduction of wash steps, leading to a faster overall extraction. This column line and corresponding universal extraction method allows for excellent recoveries of both naturally occurring opiates and various fentanyl analogues. Check out our newly developed method here.